I have done more and more with Podio recently. Podio is not so much a web app as a web app builder. Don’t ask what Podio can do for you but what could you design with Podio. But the killer feature is the app marketplace which includes all the standard apps (projects, collaborations etc) as well as community built niche apps from Twitter integration to full blown CRM (Customer Relationship Management)

I think Podio really could have something for everyone: